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I Jolanda M de Vries Selected Research

Monophenol Monooxygenase (Tyrosinase)

3/2020Autologous monocyte-derived DC vaccination combined with cisplatin in stage III and IV melanoma patients: a prospective, randomized phase 2 trial.
7/2016Adjuvant dendritic cell vaccination induces tumor-specific immune responses in the majority of stage III melanoma patients.
7/2016Immune-related Adverse Events of Dendritic Cell Vaccination Correlate With Immunologic and Clinical Outcome in Stage III and IV Melanoma Patients.
3/2016Prophylactic vaccines are potent activators of monocyte-derived dendritic cells and drive effective anti-tumor responses in melanoma patients at the cost of toxicity.
1/2016Effective Clinical Responses in Metastatic Melanoma Patients after Vaccination with Primary Myeloid Dendritic Cells.
1/2016Favorable overall survival in stage III melanoma patients after adjuvant dendritic cell vaccination.
8/2015Intranodal vaccination with mRNA-optimized dendritic cells in metastatic melanoma patients.
11/2014Long overall survival after dendritic cell vaccination in metastatic uveal melanoma patients.
3/2013Targeting of 111In-labeled dendritic cell human vaccines improved by reducing number of cells.
9/2011Route of administration modulates the induction of dendritic cell vaccine-induced antigen-specific T cells in advanced melanoma patients.
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I Jolanda M de Vries Research Topics

Disease

99Neoplasms (Cancer)
06/2022 - 09/2002
37Melanoma (Melanoma, Malignant)
01/2022 - 11/2003
7Hypersensitivity (Allergy)
11/2019 - 11/2003
3Urinary Bladder Neoplasms (Bladder Cancer)
06/2022 - 11/2012
3Inflammation (Inflammations)
10/2021 - 01/2005
3Prostatic Neoplasms (Prostate Cancer)
01/2020 - 01/2014
3Infections
01/2018 - 01/2010
3Squamous Cell Carcinoma of Head and Neck
01/2017 - 03/2005
3Communicable Diseases (Infectious Diseases)
11/2011 - 04/2010
2Rare Diseases (Rare Disease)
01/2022 - 01/2020
2Neoplasm Metastasis (Metastasis)
01/2021 - 05/2012
2Ovarian Neoplasms (Ovarian Cancer)
01/2018 - 01/2018
2Virus Diseases (Viral Diseases)
11/2012 - 07/2006
2Porcine Reproductive and Respiratory Syndrome (PRRS)
01/2010 - 04/2008
2Brain Neoplasms (Brain Tumor)
08/2009 - 07/2008
1Gestational Trophoblastic Disease (Trophoblastic Neoplasms, Gestational)
01/2022
1Choriocarcinoma
01/2022
1Hydatidiform Mole (Molar Pregnancy)
01/2022
1Testicular Neoplasms (Testicular Cancer)
01/2022
1Psoriasis (Pustulosis Palmaris et Plantaris)
10/2021
1Microsatellite Instability
05/2021
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2021
1Colitis
01/2021
1Heart Failure
03/2020
1Ascites
01/2018
1Fatigue
01/2018
1Peritonitis
01/2018
1Turcot syndrome
10/2017
1Meningoencephalitis
03/2017
1Colorectal Neoplasms (Colorectal Cancer)
10/2016
1Lymphatic Metastasis
01/2016
1Uveal melanoma
11/2014

Drug/Important Bio-Agent (IBA)

37AntigensIBA
01/2022 - 11/2003
24VaccinesIBA
01/2022 - 09/2002
16Peptides (Polypeptides)IBA
01/2018 - 11/2003
15Monophenol Monooxygenase (Tyrosinase)IBA
03/2020 - 11/2003
12Neoplasm Antigens (Tumor Antigens)IBA
01/2020 - 09/2002
9Messenger RNA (mRNA)IBA
03/2020 - 03/2005
9keyhole-limpet hemocyanin (keyhole limpet hemocyanin)IBA
01/2017 - 11/2003
8Immune Checkpoint InhibitorsIBA
01/2022 - 10/2016
8Proteins (Proteins, Gene)FDA Link
01/2018 - 07/2006
7Cancer VaccinesIBA
01/2021 - 01/2007
6Cisplatin (Platino)FDA LinkGeneric
06/2022 - 08/2011
6PlatinumIBA
01/2021 - 08/2011
6CytokinesIBA
07/2016 - 12/2007
5LigandsIBA
01/2022 - 04/2008
5Biomarkers (Surrogate Marker)IBA
01/2022 - 06/2010
3IpilimumabIBA
01/2022 - 08/2016
3Interleukin-12 (IL 12)IBA
10/2021 - 03/2005
3DNA (Deoxyribonucleic Acid)IBA
05/2021 - 04/2011
3RNA (Ribonucleic Acid)IBA
03/2017 - 07/2009
3Platinum Compounds (Compounds, Platinum)IBA
01/2017 - 08/2011
3Oxaliplatin (Eloxatin)FDA LinkGeneric
08/2016 - 07/2012
2AntibodiesIBA
01/2022 - 03/2012
2HLA-A Antigens (HLA-A)IBA
01/2022 - 03/2013
2Protamines (Protamine Sulfate)FDA Link
11/2019 - 03/2017
2Interferon Type IIBA
01/2018 - 11/2012
2ChemokinesIBA
11/2017 - 01/2016
2Death Domain ReceptorsIBA
06/2014 - 08/2011
2Monoclonal AntibodiesIBA
10/2010 - 01/2007
2Pattern Recognition ReceptorsIBA
01/2010 - 04/2008
2ferric oxide (iron oxide)IBA
04/2009 - 11/2005
2Interleukin-2 (IL2)IBA
01/2009 - 11/2002
1T-Cell Antigen Receptors (T-Cell Receptor)IBA
01/2022
1EpitopesIBA
01/2022
1Biological ProductsIBA
10/2021
1Poly(ADP-ribose) Polymerase InhibitorsIBA
05/2021
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
05/2021
1Trans-Activators (Trans-Acting Factor)IBA
01/2021
1NanovaccinesIBA
01/2021
1Granzymes (Granzyme)IBA
01/2020
1LipidsIBA
01/2018
1Interferon-gamma (Interferon, gamma)IBA
01/2018
1Immune Checkpoint ProteinsIBA
01/2018
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
03/2017
1Melanins (Melanin)IBA
03/2017
1Combined VaccinesIBA
10/2016
1VemurafenibIBA
04/2016
1Dinoprostone (PGE2)FDA Link
03/2016
1ProteomeIBA
01/2016
1CD40 Ligand (CD40L)IBA
08/2015
1Melanoma-Specific AntigensIBA
11/2014
1HMGB ProteinsIBA
06/2014
1IGF Type 2 Receptor (Insulin-Like-Growth-Factor II Receptor)IBA
06/2014
1Carboplatin (JM8)FDA LinkGeneric
06/2014
1CalreticulinIBA
06/2014
1Adenosine Triphosphate (ATP)IBA
06/2014
1sipuleucel-T (APC8015)FDA Link
01/2014

Therapy/Procedure

51Immunotherapy
01/2022 - 01/2007
25Therapeutics
01/2022 - 11/2005
6Drug Therapy (Chemotherapy)
06/2022 - 06/2010
4Lymph Node Excision (Lymph Node Dissection)
07/2016 - 09/2011
2Castration
01/2020 - 11/2019
2Treatment Delay
11/2019 - 02/2011
1Neoadjuvant Therapy
06/2022
1Cystectomy
06/2022
1Radiotherapy
01/2017
1Chemoradiotherapy
01/2017
1Intravenous Injections
03/2016
1Injections
02/2013